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Study Opposites Attract (2018)

What is the Opposites Attract study?
The Opposite Attract study is the name of the study in which serodifferent couples were monitored - one partner is HIV positive and the other negative - to assess the risk of HIV transmission in the event that an HIV positive person is on ARV therapy.

How many participants did the Opposites Attract study have?
The study included 343 serodiverse male-male couples, who were followed for 1.7 years (median), of which 80% were on ARV therapy at baseline.

What were the criteria for the participants in the Opposites Attract study?
Some of the study criteria were: sex without using condoms and PrEP, performing regular laboratory tests, using ARV therapy by the HIV-positive partner, while maintaining viral suppression at <200 copies/mL of plasma.

What are the results of the Opposites Attract study?
During more than 12,000 reported unprotected sexual relations, there was no HIV infection of any of the negative partners that could be linked to the HIV positive partner through phylogenetic testing.

The calculated estimate of the transmission rate over 100 years is 0.00 (0.00 – 1.59) for unprotected anal sex between men who have sex with men.